3M3 Whiteris G · Active for Even-Looking Tone

Brightening cream, lotion and gel formulations that reduce the look of dark spots and help skin tone look more even and radiant.

An extract of the seaweed Dictyopteris membranacea used as a skin brightener, as it acts on the three mechanisms behind skin pigmentation.

The skin pigmentation process can be summarized in three steps:

1) When exposed to UV rays, keratinocytes secrete endothelin. 2) It binds to specific receptors on the surface of melanocytes, activating melanin synthesis from tyrosine. 3) Melanin synthesis is catalyzed by tyrosinase, an enzyme controlled by a specific gene.

The mechanism of action of 3M3

Whiteris can be summarized in three points (supplier data): a) Melanosome biogenesis and maturation: first, it reduces endothelin formation, which lowers the activation of melanin synthesis.

b) Activation and synthesis of melanin within mature melanosomes. By acting on specific genes, it reduces melanosome production and size.

c) Migration of mature melanosomes along the dendrites to transfer melanin to keratinocytes. The reduction in extracellular melanin results from acting on the genes that control melanosome migration.

Storage: The optimal storage temperature for the extract is 4–18 °C/39–64 °F, protected from light; if precipitates form during storage, shake until reconstituted before adding to your formulation.

Precautions: Once the container is opened, handle the product with care to avoid secondary microbial contamination. None in particular for the user. Handling: Add it as the last ingredient of the preparation at temperatures below 50 °C/122 °F; dissolving it before use is recommended. Results have been tested in the supplier's laboratories; however, since there is no control over conditions of use, no guarantee is given for specific products, so testing is recommended for each particular application

Technical information for formulators: This sheet describes industrial uses of the raw material in the development of cosmetic products. It is not an efficacy claim for any finished product. The person responsible for the formulation must validate the concentration, compatibility and claims of their product in accordance with applicable regulations.

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